文档介绍：FT4/FT3与血肌酐作为甲状腺毒症病因鉴别指标的可行性研究
(作者:___________单位: ___________邮编: ___________)
【摘要】目的:探讨FT4/FT3鉴别亚急性甲状腺炎与Graves病的临床价值。方法:选择亚急性甲状腺炎30例与Graves病30例患者,通过对FT4/FT3、血肌酐、血沉、甲状腺摄碘率等进行分析,来获得区别亚急性甲状腺炎与Graves病的有效指标及相应切点值。结果:除FT4在两组间差异无统计学意义外(P >),FT3、FT4/FT3、血肌酐、血沉、甲状腺摄碘率两组间差异均有统计学意义(P<)。以FT4/FT3值≥,%、%。以SCr≥60 μmol/L来诊断亚急性甲状腺炎与Graves病时,%、%。结论:FT4/FT3是区别亚急性甲状腺炎与Graves病的有效指标,对于甲状腺毒症患者当FT4/FT3≥,要考虑亚急性甲状腺炎可能。血肌酐对于鉴别两者也有一定的价值。
【关键词】亚急性甲状腺炎 Graves病甲状腺毒症 FT4/FT3 血肌酐
[Abstract] Objective: To make a distinction between subacute thyroiditis and Graves
’ disease with some simple and pratical parameters. Methods: 30 patients with subacute thyroiditis and 30 with Graves’ disease were studied. Through analysis of FT4/FT3 ratio, serum creatinine(SCr), erythrocyte sedimentation rate(ESR) and radioactive iodine uptake (RAIU), the valuable parameters and the relevant cutoff values to differentiate subacute thyroiditis from Graves’ disease were got. Results: FT3, FT4/FT3 ratio, SCr, ESR and RAIU were significantly different between subacute thyroiditis and Graves’ disease(P<), FT4 no significantly different between the two groups(P >). The cutoff values of FT4/FT3 ratio and of subacute thyroiditis and Graves’ disease were and 60 μmol/L respectively. The sensitivity and specificity of the former were % and %,