文档介绍：Spectral domain-optical coherence tomography
to detect localized retinal nerve fiber layer
defects in atous eyes◊
Gianmarco Vizzeri, Madhusudhanan Balasubramanian, Christopher Bowd, Robert N.
Weinreb, Felipe A. Medeiros, Linda M. Zangwill*
Hamilton a Center and Department of Ophthalmology, University of California, San Diego,
La Jolla, California, USA.
*Corresponding author: ******@
Abstract: This study examines the ability of RTVue, Cirrus and Spectralis
OCT Spectral domain-optical coherence tomographs (SD-OCT) to detect
localized retinal nerve fiber layer defects in atous eyes. In this
observational case series, four a patients (8 eyes) were selected
from the University of California, San Diego Shiley Eye Center and the
Diagnostic Innovations in a Study (DIGS) based on the presence of
documented localized RNFL defects in at least one eye confirmed by
masked stereophotograph assessment. One RTVue 3D Disc scan, one
RTVue NHM4 scan, one Cirrus Optic Disk Cube 200x200 scan and one
Spectralis scan centered on the optic disc (15x15 scan angle, 768 A-scans x
73 B-scans) were obtained on all undilated eyes within a single session.
Results pared with those obtained from stereophotographs. In 6
eyes the presence of localized RNFL defects was detected by
stereophotography. In general, by qualitatively evaluating the retinal
thickness maps generated, all SD-OCT instruments examined were able to
confirm the presence of localized atous structural damage seen on
stereophotographs. This study confirms SD-OCT is a promising technology
for a detection as it may assist clinicians identify the presence of
localized atous structural damage.
2009 Optical Society of America
OCIS codes: () Optical coherence tomography; () Optical diagnostics for
medicine
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Datasets associated with this article are available at http://hdl./10376/1370.
References and links
1. D. H