文档介绍：地黄不同炮制品补血作用研究
作者:崔瑛,房晓娜,王会霞,李军
【摘要】目的观察地黄的3个炮制品对血虚小鼠的补血作用。方法应用环磷酰胺腹腔注射和综合放血造成小鼠血虚模型,观察地黄不同炮制品对血虚小鼠外周血象、CFU-E、BFU-E和CFU-GM的影响。结果与酒炖熟地组相比,生地组明显增强血虚小鼠骨髓粒系祖细胞的生成能力,并能升高外周血白细胞数;其他各组相比,酒炖熟地组显著增强血虚小鼠骨髓红系祖细胞的生成能力。结论不同地黄炮制品对血虚小鼠补血作用是通过不同的机制实现的。
【关键词】生地黄; 清蒸熟地; 酒炖熟地; 血虚; 补血
Abstract:ObjectiveTo study the effects of three different processed products of Dihuang on blood deficiency of mice. Methods The blood deficient models in mice were induced by intraperitoneal injection of cyclophosphamide or by limiting diet and chronic bleeding . Three different processed products of Dihuang were used in treating the models and the effects on the peripheral blood of the mice of blood deficiency and on the CFU-E,BFU-E and CFU-GM were observed. ResultsRadix Rehmanniae enhanced capacity of proliferation of granulocyte progenitor cell and increased the total numbers of WBC; Radix Rehmanniae praepared by yellow wine stewing enhanced capacity of proliferation of erythroid progenitor different processed products of Radix Rehmanniae can enrich the blood by different mechanism.
Key words:Radix Rehmanniae; Prepared rhizome of rehmannia by steam; Radix Rehmanniae prapared by yellow wine stewing; Blood deficiency; Enrich the blood
地黄为玄参科植物地黄Rehmannia glutinosa Libosch. 的块根[1],始载于《神农本草经》,被列为上品。历代本草均有记载,为常用中药之一。由于炮制方法的不同,有鲜地黄、生地黄及熟地黄等不同品种。生地黄性寒,具有清热凉血、养阴生津的功效,制后可使药性由寒转温,味由苦变甘,功效由清