文档介绍：
Investigating the effects of side chain length on the AIE
properties of water-soluble TPE derivatives#
Dong Yifan1, WANG Weilun1, ZHONG Cewen1, SHI Jianbing1, TONG Bin1, FENG
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Xiao2, ZHI Junge2, DONG Yuping1**
(1. School of Materials Science and Engineering, Beijing Institute of Technology;
2. School of Chemistry, Beijing Institute of Technology)
Abstract: The emissive properties of fluorophores in aggregated state are important for the
development of bio-sensors or bio-imaging reagents. So three water-soluble TPE derivatives with
different length of side chains have been synthesized and investigated the effects of side chains on
aggregation-induced emission (AIE) properties in the aggregated states. The results indicate that side
chains on the fluorophores play a pivotal role on their emission in aggregated state mediated by heparin
or solid state, due to the coplanarity of these TPE derivatives was affected by side chains. The rates of
radiative decay kf and non-radiative decay knr have been obtained through the quantum yields and
lifetime, and a larger kf and smaller knr were present pound TPE-C4N, suggesting that the
aggregated TPE-C4N should posses the most remarkable fluorescent property.
Key words: Organic Solid; Tetraphenylethylene (TPE); Aggregation-Induced Emission (AIE);
Fluorescence Enhancement; Heparin
Introduction
The development of fluorescent probes for the detection of biomacromolecules has been a
fervid research field, presumably because of their possibility to be revolutionarily applied in
bioscience and biotechnology engineering.[1] Generally, fluorescent bio-probes possess remarkable
advantages such as low background noises, high sensitivity, ease of operation, and broad working
scope.[2-3] Among the fluorescent bio-probes reported so far, the most attractive ones are the
“turn-on” or “light-up” sensors due to their excellent availability and reliability. Particularly,
signal produced b