文档介绍：消化道恶性肿瘤患者化疗期抑郁发生情况及相关因素的探讨
鞠斐张渝袁昌琼
解放军总医院南楼消化科 100853
【摘要】目的:探讨消化道恶性肿瘤患者化疗期抑郁的发生情况及相关因素。
方法:采用Zung氏抑郁自评量表(SDS)、一般自我效能量表(GSES)、简易应对方式问卷量表(SCSQ)、社会支持评定量表(SSRS)及自设问卷评价66例化疗期的消化道恶性肿瘤患者抑郁发生情况,并分析其相关因素。结果:37例(%)患者出现抑郁症状,有无医疗负担、化疗的疗程、效果以及副作用均与抑郁发生率相关。患者的抑郁程度与简易应对方式问卷量表中消极应对维度得分呈正相关(P<),与一般自我效能量表得分、社会支持评定量表总分、客观支持得分、主观支持得分、对支持的利用度和简易应对方式问卷量表中积极应对维度得分均呈负相关(P<)。结论:消化道恶性肿瘤患者化疗期抑郁发生率高,与多种因素相关。
【关键词】消化道恶性肿瘤化疗抑郁
The Exploration of Depression Occurrence and Correlation Factors on Patients with Digestive Tract Malignant Tumor During Chemotherapy
【abstract】Objective: To explorate the occurrence and correlation factors of depression on patients with digestive tract malignant tumor during chemotherapy. Method: Sixty-six patients with digestive tract malignant tumor during chemotherapy were investigated with Zung’s Self-Rating Depression Scale (SDS), general self-efficacy scale (GSES), simple coping style questionnaire (SCSQ), social support rating scale (SSRS) and self-develop questionnaire to estimate the depression occurrence and its correlation factors. Result: thirty-seven patients (%) occurred depression which was correlated with whether they had medical burden, and the period, effect plication of chemotherapy. The degree of depression was positively related to the negative coping score of SCSQ (P<), negatively related to the score of GSES, the total score of the SSRS, subjective support score, objective support score, the support exploitability and the positive coping score of SCSQ (P<).
Conclusion: Patients with digestive tract malignant tumor during chemotherapy have a higher occurrence rate of depression which was relate to multiple factors.
【Keyword】: digestive tract malignant tumor chemotherapy depression
消化系统恶性肿瘤是我国常见的、多发的、死亡人数较多的恶性肿瘤之一。恶性肿瘤是目前病死率较高的疾病,在其诊断和治疗过程中,患者可能经历一系列复杂的心理问题,常见的是焦虑和抑郁【1】,其中抑郁是癌症患者最常见的心理危机【2】。研究表明,癌症患者的情绪异常对预后影响极大,抑郁状态可加重治疗的副作用,也能促进癌症的复发转移、恶化等,还会降低生活质量以及导致就诊次数增加、住院时间延长、治疗依从性差及增加医疗费用等【3,4】。化疗是目前治疗癌症的主要手段之一,但任何化疗药物均有