文档介绍：高血压病患者代文治疗前后血浆纤维蛋白原和血清钾浓度的变化            作者:朱秀龙魏芝宝时间:2007-11-2212:41:00                     【关键词】 高血压摘要:目的:为观察高血压病患者代文(缬沙坦胶囊)治疗前后血浆纤维蛋白原[Fbg]和血清钾浓度的变化。方法:采用热浸淀比浊法和全自动生化分析仪分别测定23例正常人和53例高血压病患者代文治疗前和治疗12周后的血浆Fbg和血清钾浓度。结果:治疗前高血压病患者的血浆Fbg浓度明显高于正常人(±±,P<),而血清钾浓度明显低于正常人(±±,P<);±,P<),而血清钾浓度无明显变化(P>)。结论:提示高血压病患者的血浆Fbg水平升高而血清钾浓度偏低,代文在降低血压的同时降低血浆Fbg水平,但对血清钾浓度影响不大。关键词:高血压病;纤维蛋白原;血清钾;代文 ChangesofPlasmaFibrinogenandSerumK+ConcentrationinPatientswithEssentialHypertensionBeforeandAfterDiovanTreatment Abstract:Objective:To investigatethechangesofplasmafibrinogenandserumK+andconcentrationinpatientswithessentialhypertensionbeforeandafterdiovan(CapsValsartan):PlasmafibrinogenandserumK+:Thebaselineconcentrationsofplasmafibrinogenweresignificantlyhigherinhypertensivepatientsthan in nomotonsive controls(±±,P<).whilethelevelsofserumK+ werelowerinhypertensivepatiensthaninnormotensivecontrols (±.7±,P<).After12weekstreatmentofDiovan,±(P<).whileserumK+concentrationsdidn’: