文档介绍：--------------------------校验:_____________-----------------------日期:_____________尿路感染大肠埃希菌耐药分析尿路感染大肠埃希菌耐药分析闫雳[作者单位]安徽省萧县人民医院检验科,235200[摘要]目的:探讨尿路感染中大肠埃希菌的耐药性变迁,为临床合理用药提供试验依据。方法:对2008~2010年度尿标本检出的234份大肠埃希菌进行超广谱β-内酰***酶(ESBLs)检测和药敏试验,并对药敏结果进行分析。结果:大肠埃希菌的产酶率呈增高趋势;药敏结果显示大肠埃希菌除对亚***培南耐药率为0外,对其他常用抗菌药物均出现了不同程度的耐药性,且ESBLS(+)的细菌耐药率普遍高于ESBLs(-)细菌。结论:尿路感染的大肠埃希菌耐药现象严重,尤其是ESBLs(+)株,要不断加强耐药性检测,为临床合理用药提供参考。[关键词]尿路感染;大肠埃希菌;药敏试验;超广谱β-内酰***酶[中图分类号1[文献标识码]ATheanalysisofdrugresistanceofEscherichiacoliinurinarytractinfectionsYanLi(DepartmentofClinicalLaboratory,XiaoxianPeople'sHospital,XiaoxianAnhui235200,China)\[Abstract]Objective:ToexploringtheresistancechangesoftheEscherichiacoli()inurinarytractinfection,:Twohundredandthirty–fouestrainsofin2008to2010annualurinespecimenwithextended-spectrumβ-lactamase(ESBLs)detectionanddrugsusceptibilitytest,weredetected,,andthedrugsusceptibilityresultswereanalyzed..Results:therateofedarisingtrend;thedrugsensitivitytestshowsthattheresistanceexistsinnormalantibioticswasindifferentdgreesexpectforImipenem,,andtherateofmedicalresisitanceinESBLs(+)bacteriawashigherthaninESBLs(-).Conclusions:. especiallyin ESBLs(+) strains,,whichprovidethereferencesforthecliniclrationaldruguse.[Keywords]urinarytr