文档介绍：穴位肥大细胞及其颗粒物 在针刺镇痛中的作用
Outline
穴位肥大细胞在针刺镇痛效应中的作用
穴位胶原纤维在针刺镇痛效应中的作用
穴位注射组胺的镇痛效应
手针和电针穴位信号的启动机制
Mast cells in acupoints and sideward
Comparison of Number of MCs in Zhushanli and non-acupoints of Rat
Group Name
MCs Number
Skin
Muscle
Acupoint
(n=6)
±
±
Non-acupoint
(n=6)
±*
±*
THE JOURNAL OF SCIENCE & HEALING, 2008,4(3),170-177
1. The relationship between mast cell function and acupuncture effect
Animal model :AA (acute arthritis) Rat
Complete Freunds’ adjuvant
Acupoint selected: Zushanli (ST36)
D
ST 36
C
1. The relationship between mast cell function and acupuncture effect
Treat effect:
Ease pain,Pain threshold
1. The relationship between mast cell function and acupuncture effect
The degranulation of mast cells
SD Rats
Tail Flick Model
Anatomy Position of Zusanli
Acupuncture
Injection drugs for prevent degranulation of MC
A
B
D
E
ST 36
C
Pain threshold of rat when shield mast cell degranulation
1. The relationship between mast cell function and acupuncture effect
ID
Group Name
组别
Average ± SEM (%)
A
Control
正常对照组
–±
B1
Acupuncture at ST36
穴位针刺组
±*
B2
Acupuncture at Nearby-ST36
旁开针刺组
±*△△
C1
Injection of DSCG at ST36
色甘酸钠注射组
±*△
C2
Injection of NaCl at ST36
生理盐水注射组
±*△
D1
Acupuncture after DSCG at ST36
色甘酸钠注射+针刺组
±*△△
D2
Acupuncture after NaCl at ST36
生理盐水注射+针刺组
±*▲
D3
Acupuncture opposite side after DSCG
色甘酸钠注射+对侧针刺组
±*▲▲
各组别大鼠痛阈变化率峰值比较(20分钟时)(n=6)
Note: *P< vs. Group A; △P<, △△P< vs. Group B1; ▲P<, ▲▲P< vs. Group D1
1. The relationship between mast cell function and acupuncture effect
Group Name
组别
MC Degranulation Ratio (Average ± SEM) (%)
Skin
Muscle
Control
正常对照组
±
±
Acupuncture
穴位针刺组
±*
±**
Acupuncture after DSCG
色甘酸钠注射+针刺组
±△
±
Acupuncture after NaCl
生理盐水注射+针刺组
±*
±
穴区组织肥大细胞脱颗粒率统计(n=6)
Note: *P<, **P< vs. Contr