文档介绍:Cytoskeleton and motile of cellsCell movements: Whole cell movement; cell shaping; Intracellularmovements; membrane cell movement1)Swimming cilla and flagella2)otion -Amoeboid motionEctoplasm ( cortical zone ) MF gelazation pushand MF/myosin3)otion-fibroblastic movementCell-substratum interaction and role of stress fibersInitial spreading: filopodia, ruffles, pseudopodia,lamellipodium ----MFPolarization ---MT and MTOCTranslocation---- MF, --MF, MT, IF and the interaction ofcytoskeleton with plasma contractility1)Muscle contraction-sliding -filament ere and myofibril Thick filament--- Myosin Thin filament--Actin filamemt Tropomyosin Troponin TnC, TnI TnT?-actinintitin 3 millionThe molecular basis of contractionmyosin head rapidly bends toward the center of ere, moving actin filament 5-15 nm Rigid "lever arm" of myosin neck The energetic of filament sliding---a model of theactinomyosin contractile cycle-ATP/ADP Excitation-contraction-coupling--Neuromusclarjunction The role of tropomyosin in muscle contracyionand Ca2+/troponin2)Nonmuscle contraction Stress fiber Actin/myosin and assembly and disassemblyofcytoskeleton Centrosome/ ochoreContractile ring