文档介绍：高效液相色谱法测定曲美胶囊中盐酸西布曲明的含量高效液相色谱法测定曲美胶囊中盐酸西布曲明的含量高效液相色谱法测定曲美胶囊中盐酸西布曲明的含量曹文丁,余佳文z,官柳2肖礼娥.(,重庆市400015;,重庆市408000)—0408(2004)04—0240—02摘要目的::分析柱为DiamonsilCld250mm×,5m),流动相为甲醇一水一三乙***(75:25:),检测波长为223nm,:--,%,%.结论:本法检测快速,定量准确,;盐酸西布曲明;高效液相色谱法;AOWending(ProductDepartment,TaijiGroup,Chongqing400015)YUJiawen,GUANLiu,XIAOLi'e(TheThirdInstituteofAcademyofPharmacy,TaijiGroup,Chongqing408000)ABSTRACTOBJ『ECTIVE::StationaryphasewasDiamonsilCl8(;5ttm),mobilephasewasmixtureofmethanol—H—triethylamine(75:25:,v/v),detectionwavelength223nm,:Therewasgoodlinear-itywithintheconcentrationrangeof()mg/mlforsibutraminehydrochloride,theaveragerecoveryofsibu—%(%).CONCLUS10N:urate,;sibutraminehydrochloride;HPLC;content曲美胶囊在临床上主要用于治疗单纯性肥胖症,,笔者进行了定量研究,,包括智能柱温箱,自动进样器,(太极集团涪陵制药厂);盐酸西布曲明胶囊(曲美,太极集团涪陵制药厂);甲醇为色谱纯,:DiamonsilC18(250mm×,5m);流动相:甲醇一水一三乙***(75:25: