文档介绍：左旋甲状腺素钠治疗对亚临床甲状腺功能减退患者血脂影响【摘要】目的:观察亚临床甲状腺功能减退症患者经左旋甲状腺素钠治疗后血脂的变化。方法:亚临床甲状腺功能减退症患者40例,〜50卩g,观察治疗前后促甲状腺素,游离甲状腺素,游离三碘甲状腺原氨酸,甲状腺过氧化物酶抗体和甘油三酯、胆固醇、低密度脂蛋白、高密度脂蛋白及临床症状。结果:有甲减症状的部分患者症状缓解,血甘油三酯、胆固醇、低密度脂蛋白较治疗前明显降低()。结论:左旋甲状腺素钠治疗可使亚临床甲减患者症状缓解,血脂改善。【关键词】左旋甲状腺素钠;亚临床甲状腺功能减退症;血脂文章编号:1009-5519(2007)23-3495-02中图分类号:R5文献标识码:AEffectofL-reatmentonserumlipidinthepatientswithsubclinicalhypothyroidismWANGDong,CHENXia,CHENJun-jian,etal.(DepartmentofEndocrinology,TheAffliatedHospitalofJiangsuUniversity,Jiangsu212001,China)[Abstract】0bjective:ToobservethechangeofserumlipidfollowingL-reatment・Methods:40subclinicalhypothyroidismcasesweretreatedwithL-、,thyroidstimulatinghormone,thyroidperoxidaseantibody,totalcholesterol,triglyceride,lowdensitylipoproteincholesterol,:,thelevelsoftotalcholesterol,triglyceride,lowdensitylipoproteincholesterolwerelowerthanthosebeforetreatment()・Conclusion:ThetreatmentofL-thyroxinehormonecanameliorateclinicalsymptomsandimprovelipidprofile.【Keywords】hyroidhormone;Subclinicalhypothyroidism;Bloodlipid亚临床甲状腺功能减退症简称亚临床甲减,是以血液中促甲状腺素(TSH)水平升高,而游离甲状腺素(FT4)、游离三碘甲状腺原氨酸(FT3)在正常范围为特点的内分泌性疾病。其通常无症状或仅有轻微症状,%~10%[1],其中老年人发病率更高。亚临床甲减是否能引起明显的靶组织及靶器官损害,是否值得激素替代或补充