文档介绍：Advanced Free Radical Reactions for
Organic Synthesis
Elsevier, 2004
Author(s): Hideo Togo
ISBN: 978-0-08-044374-4
Preface, Page vii
List of Abbreviations, Pages xi-xii
1 - What are Free Radicals?, Pages 1-37
2 - Functional Group Conversion, Pages 39-56
3 - Intramolecular Radical Cyclizations, Pages 57-121
4 - Intermolecular Radical Addition Reactions, Pages 123-156
5 - Alkylation of Aromatics, Pages 157-170
6 - Intramolecular Hydrogen-Atom Abstraction, Pages 171-185
7 - Synthetic Uses of Free Radicals for Nucleosides and Sugars: Barton-
bie Reaction, Pages 187-197
8 - Barton Decarboxylation Reaction with N-Hydroxy-2-thiopyridone, Pages 199-
213
9 - Free Radical Reactions with Metal Hydrides, Pages 215-218
10 - Stereochemistry in Free Radical Reactions, Pages 219-230
11 - Free Radicals Related to Biology, Pages 231-246
12 - Free Radicals for Green Chemistry, Pages 247-256
Index, Pages 257-258
Preface
This book covers the fundamental properties anic free radicals and their synthetic
uses. It consists of twelve chapters, starting from fundamentals and physical properties of
organic free radicals, reduction and functional group conversion, cyclization, addition,
alkylation onto aromatics, Barton reaction and related reactions, Barton-bie
reaction, Barton decarboxylation, free radical reaction with metal hydrides, stereo-
selective free radical reactions, free radicals in biology, and free radicals for green
chemistry. The important factors in these free radical reactions are some radical specific
reactions, as mentioned in each chapter. Since the basic study on free radical reactions
has been established by Barton, Ingold, Stork, Beckwith, Giese, etc., free radical
reactions have e an increasingly important and attractive tool anic synthesis,
especially in the last two decades. Recently, in addition to a typical but toxic radical
reagent, . tributyltin hydride, muc