文档介绍：摘要膨胀床综合了流化床和填充床吸附的优点,具有返混小、柱效高的显著特点。可以把生物和医药制品下游处理过程中的预处理、浓缩和产物捕获等几个步骤集成于一个单元操作中,从而将离心、过滤、层析纯化等步骤集中在一个单元完成。因而大大简化了提纯工艺,提高了产品收率,降低了分离成本。但要使膨胀床真正成为一种重要的分离手段,必须对膨胀床的基本特性有明确的理解,譬如流体力学性能、膨胀率、混合性能、分离效率等,这些都是膨胀床操作时的重要参数, 也是膨胀床进行流程优化和工程放大设计时所需的基础参数。本文将进行膨胀床中局部固含率径向不均匀分布的研究。本课题以密度与液相密度相近的大孔弱碱性苯乙烯系树脂D301R为固相, 以自来水为液相,D图像采集处理技术,对液固膨胀床中径向局部固含率分布进行研究。结果表明,膨胀床中局部固含率径向分布并不均匀,沿床中心向床壁面逐渐增加,在相对径向位置r/R=,然后逐渐减小。另外,在本文中以环核模型为基础,引入颗粒一流体系统表观粘度和粒子群曳力系数等参数,运用受力平衡原理,建立了描述液固膨胀床充分发展段径向局部固含率分布规律的数学模型,所建模型模拟值与实验值的平均相对误差为 %,模型能较好地预测液固膨胀床中局部固含率的径向分布。但是,所建模型的使用范围有一定的局限性(1<Re。(20),当Re。的值超过一定范围的时候, 模型所做出的预测值与实际值存在较大的误差,还有待进一步研究。关键词i液固膨胀床;径向分布;局部固含率;模型 ABSTRACT Expanded bedadsorption但BA),wim themerits of both fluidizedbed and packed bedadsorption,due toitssimplieity∞a single step operation,lower back mixing. costreduction anovel technique and ing inereasingly investigations,such asexpansion ratio,hydrodynamic performance, separating efficiency,ale ofgreatimpor[ance inoptimum design,andanderstanding, analyzing and predicting plex absorptionrH'formance inEBA,However,the accuracy descfiption ofitscharacteristic isstill adifficult taskand theapplication is investigation OU theradialdistributionofadsorbent particles willbe discussed inthispaper. Inthispaper,Styrene-DVB D301R Was usedas solidphase and theliquidphase was tap solidholdups weremeasured byusing allimprovedmicro—conductivity probe technique and D measuring system in a ID and hi【gh liquid-solidexpanded localradialsolidholdup increasedwiththevalue of the—Randreached themaximum when thevaluPofr,Rwas about -. Inaddition,a radialdistribution model ofsolid holdups in aliquid—solidexpanded bed Wasdeveloped Oilthebasis oftheoore- isobtained between themodelpredictions andtheexperimental values ofthe radialdistributions. The average relaftve error between thepredictions aadmeasured data %.n碡 results