文档介绍：.页眉. .页脚. 非小细胞肺癌脑转移的药物治疗【摘要】近年来,非小细胞肺癌脑转移的发病率逐年上升,严重危害着人类的生命安全。表皮生长因子受到( epidermal growth factor receptor, EGFR )体酪氨酸酶抑制剂分子靶向治疗的出现让非小细胞肺癌的研究得到突破,使得 EGFR 小分子抑制剂成为靶向治疗的热点。同时,第三代药物的单药化疗如紫杉醇脂质体等单药对于晚期非小细胞肺癌患者的效用也逐渐被认可。本文力从表皮生长因子受体这个肿瘤学药物研发的一个重要靶点的研究以及药物治疗上,对非小细胞肺癌脑转移治疗进行探讨。关键字:非小细胞肺癌转移靶向治疗研究 Non-small cell lung cancer with brain metastasis drug therapy 【 Abstract 】 In recent years, non small cell lung cancer with brain metastasis incidence increased year by year, seriously endangering the safety of human life. Epidermal growth factor ( epidermal growth factor by receptor, EGFR )body tyrosinase inhibitors targeted molecular therapy appears tonon small cell lung cancer has been a breakthrough, make EGFR small molecule inhibitors as targeted therapy of hot. At the same time, the third generation drug such as the single agent chemotherapy of paclitaxel liposome as monotherapy for patients with advanced non-small cell lung cancer is gradually being recognized. This article from the epidermal growth factor receptor in the oncology drug development is an important target for research and drug therapy for non small cell lung cancer, brain metastases treatment to explore. Key words: Non small cell lung cancer transfer targeted therapy research 肺癌是人类常见的恶性肿瘤之一,对人类死亡威胁率居男性死亡之首,女性死亡率仅次于乳腺癌。非小细胞肺癌( non-small cell lung cancer, NSCLC )占据肺癌的 80% ,早中期发生淋巴结转移、邻近组织以及器官的浸润,治疗困难。患者患病期间 5 年与 10 年的生存率分别是