文档介绍：534 trends in analytical chemistry, vol. 21, no. 8, 2002
Solid-phase microextraction (SPME) for rapid
field sampling and analysis by gas
chromatography-mass spectrometry (GC-MS)
Gary L. Hook, Gregory L. Kimm, Tara Hall, Philip A. Smith*
Uniformed Services University of the Health Sciences, Department of Preventive Medicine
and Biometrics, Bethesda, MD, USA
Modern gas chromatography-mass spectrometry 1. Introduction
(GC-MS) methods and equipment, with the sensi-
tivity and structural information these methods pro- In both the civilian and munities,
vide, make GC-MS an excellent choice for field there is growing demand for rapid field analysis
detection and identification of a range anic of volatile and semi-pounds
chemicals. Numerous sampling techniques allow [1,2,3,4]. Analytical instrumentation for detec-
detection of GC-MS analytes in environmental tion and identification of pounds has
matrices, although multiple sample-handling steps e smaller, more reliable, and increasingly
and use of extraction solvents increase plex- sensitive. Gas-chromatography (GC) tools have
ity and time needed plete analyses. Solid- undergone important improvements such as
phase microextraction (SPME) has been shown to development of open tubular columns with
be suitable for sampling environmental con- bonded stationary-phase material, providing
taminants from air, water and soil for G