文档介绍：Special Article
Clinical practice guideline: Red blood cell transfusion in adult
trauma and critical care*
Lena M. Napolitano, MD; Stanley Kurek, DO; Fred A. Luchette, MD; Howard L. Corwin, MD;
Philip S. Barie, MD; Samuel A. Tisherman, MD; Paul C. Hebert, MD, MHSc; Gary L. Anderson, DO;
Michael R. Bard, MD; William Bromberg, MD; William C. Chiu, MD; Mark D. Cipolle, MD; PhD;
Keith D. Clancy, MD; Lawrence Diebel, MD; William S. Hoff, MD; K. Michael Hughes, DO;
Imtiaz Munshi, MD; Donna Nayduch, RN, MSN, ACNP; Rovinder Sandhu, MD; Jay A. Yelon, MD;
for the American College of Critical Care Medicine of the Society of Critical Care Medicine and the Eastern
Association for the Surgery of Trauma Practice Management Workgroup
Objective: To develop a clinical practice guideline for red blood proved by the EAST Board of Directors, the Board of Regents of the
cell transfusion in adult trauma and critical care. ACCM and the Council of SCCM.
Design: Meetings, teleconferences and electronic-- Results: Key mendations are listed by category, including
munication to achieve grading of the published evidence, discus- (A) Indications for RBC transfusion in the general critically ill patient;
sion and consensus among the mittee members. (B) RBC transfusion in sepsis; (C) RBC transfusion in patients at risk
Methods: This practice management guideline was developed by for or with acute lung injury and acute respiratory distress syn-
a joint taskforce of EAST (Eastern Association for Surgery of Trauma) drome; (D) RBC transfusion in patients with neurologic injury
and the American College of Critical Care Medicine (ACCM) of the and diseases; (E) RBC transfusion risks; (F) Alternatives to RBC
Society of Critical Care Medicine (SCCM). We performed pre- transfusion; and (G) Strategies to reduce RBC transfusion.
hensive literature review of the topic and graded the evidence using Conclusions: Evidence-based mendations regarding the
scientific assessment methods employed b