文档介绍：第42卷第3期
2012年5月
温州医学院学报
Journal of Wenzhou Medical College
I论
著l
三唑类席夫碱的绿色合成和生物活性研究
孙庆庆,王敏,沈淑娇,徐洪良,叶晓霞
(温州医学院药学院,浙江温州325035)
[摘要]目的:绿色合成三唑类席夫碱并进行调节植物生长活性研究。方法:以水、乙醇为溶剂代替传
统方法中采用的强碱KOH。绿色合成了17个三唑类席夫碱化合物,选取双子叶植物萝P种子和单子叶植物
小麦种子进行调节植物生长活性测试。结果:经红外光谱、质谱、磁共振氩谱与碳谱确证了17个化合物
的结构;化合物4和5为新化舍物。活性测试表明:化合物l一8对双子叶植物生长有明显的促进作用。化
合物9—17对双子叶植物生长表现为促进或抑制作用。化合物I—17对单子叶植物生长表现为促进或抑制
作用。结论:、操作简单特点;合成化合物在不同浓度
下均具有较强的促进或抑制植物生长作用,尤其是化合物1和8在10 ug/mL时,对双子叶植物生长有明显
的促进作用;化合物6和7在lo¨g/mL时,对单子叶植物生长有较强的促进作用;这类化合物有望开发成
植物生长促进剂。
[关键词]
三唑类席夫碱:绿色合成;活性测试
[中图分类号][文献标志码]A[文章编号]1000—2138(2012)03-0218一06
A
synthesis end
biological
evaluation
of
triazole
schlff
beses
SUN
Oingqing.
of
№dical
C011ege.
Objective;To
synthesize
schiff
bases bearing triazole
in
and
plant—growth regulating
effects of
the title
:pounds
(1—17)were
prepared
in
ethanol
sovlent in place
of
KOH,which
used
in
the
traditional
activity
of
pounds
the vegetative
growth of
wheat and
redish
plant
;All
synthesized products
determined
by
。
IH NMR and 13c
pounds
4 and 5
pounds
I一8
showed
obvious promoting effect
the growth
of
radish
9—17 indicated promoting
inhibiting
the growth
of
radish
synthesized products
displayed
promoting
inhibiting activities
the growth of
wheat with
the reported
research,nor
adopted
is
simple,easily handle
and
compounds had
inhibiting
effect
plant
in
lO
pg/mL
100
ug/,products
l and
8 expressed
promoting activities
the growth of
radish plant in
10懈/mk
compounds
6 and
7 reflected distinct
promoting
activities
the growth of
wheat plant
in
10“g/mL.
pounds
be
develop