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中华胸心血管外科杂志 2003 年 8 月第 19 卷第 4 期 Chin J Thorac Cardiovasc Surg ,August 2003 ,Vol. 19 No. 4 · 922 ·
·实验研究·
肺减容手术用国产牛心包垫片的研制
王俊杨帆刘彦国李剑锋刘军
【摘要】目的研制开发肺减容手术用可替代昂贵进口产品的国产牛心包垫片,并初步验证其应用
的可行性。方法精选 2~3 岁鲁西南牛或秦川牛之心包,经特殊处理加工后制成 3 种不同厚度并呈“鞘
状”的肺减容手术用牛心包垫片(A1 、A2 、A3) 。利用犬模型对其进行评判和筛选,选取操作性能(包括钉合、
切割及装卸 3 方面) 及切缘耐压作为评判指标。结果 3 种型别的产品多数功能指标满足要求,其中 A3 组
产品最适合临床使用。结论肺减容手术用国产牛心包垫片在动物实验中显示了良好的性能,具有推广
临床试用的价值。
【关键词】肺气肿肺切除术生物相容性材料牛心包片
Experimental study of home made bovine pericardium buttressing the staple line in lung volume reduction surgery WA N G
J un , YA N G Fan , L IU Yan guo , et al . Division of Thoracic S urgery , Peking U niversity People’s Hospital , Beijing
100044 , China
【Abstract】Objective : To invent the cost efficient home made bovine pericardium buttressing the staple lines in lung volume
reduction surgery , and evaluate its feasibility by the means of animal test . Methods : the bovine pericardium of certain type of
cattle was chosen , and special management was applied on it , making a sheath like product especially for LVRS. A serial types
named A1 , A2 and A3 were prepared for the dog model pre clinical experimental test . The smoothness of stapling and dividing ,
the effectiveness of sealing , and the endurance of pressure were recorded as the index of judgment . Results : Products of all these
t