文档介绍：周围动脉疾病治疗指南
解 读
1
Class I Benefit >>> Risk
Procedure/ Treatment SHOULD be performed/ administered
Class IIa Benefit >> Risk Additional studies with focused objectives needed
IT IS REASONABLE to perform procedure/administer treatment
Class IIb Benefit ≥ Risk Additional studies with broad objectives needed; Additional registry data would be helpful
Procedure/Treatment
MAY BE CONSIDERED
Class III
Risk ≥ Benefit No additional studies needed
Procedure/Treatment should NOT be performed/administered SINCE IT IS NOT HELPFUL AND MAY BE HARMFUL
should
is recommended
is indicated
is useful/effective/ beneficial
is reasonable
can be useful/effective/ beneficial
is probably recommended or indicated
may/might be considered
may/might be reasonable
usefulness/effectiveness is unknown /unclear/uncertain or not well established
is not recommended
is not indicated
should not
is not useful/effective/beneficial
may be harmful
推荐级别及证据分级
2
Class I Benefit >>> Risk
Procedure/ Treatment SHOULD be performed/ administered
Class IIa Benefit >> Risk Additional studies with focused objectives needed
IT IS REASONABLE to perform procedure/administer treatment
Class IIb Benefit ≥ Risk Additional studies with broad objectives needed; Additional registry data would be helpful
Procedure/Treatment
MAY BE CONSIDERED
Class III
Risk ≥ Benefit No additional studies needed
Procedure/Treatment should NOT be performed/administered SINCE IT IS NOT HELPFUL AND MAY BE HARMFUL
Level B 单中心随机对照研究；或非随机性研究
推荐级别及证据分级
Level A 经过多中心随机对照研究得到的一致性结论
Level C 无随机对照研究的专家共识或制定的治疗规范。
3
危险因素
PAD主要病因是动脉粥样硬化。
导致动脉粥样硬化的危险因素包括（吸烟、糖尿病、血脂异常、高血压、高同型半胱氨酸血症、C反应蛋白升高）
4
危险因素
5
高危人群
年龄大于70岁
年龄大于50，小于70岁，有糖尿病或吸烟史
年龄小于50岁，患糖尿病，同时合并（吸烟史；血脂异常；高血压；高同型半胱氨酸血症）任一危险因素
既往有冠脉、脑血管或肾血管动脉硬化病史
6
自然病程
Limb
Morbidity
Cardiovascular Morbidity / Mortality
Worsening Claudication 10-20%
Critical Limb Ischemia
1-2%
Nonfatal CV Events
20％
Mortality 15-30%