文档介绍：胰腺疾病英文
胰腺疾病英文
解剖
头，颈，体，尾，钩突。
主胰管 (duct of Wirsung)
副胰管 (duct of Santorini)
胰腺分泌
外分泌Exocrine
内分泌Endocrine B,A,D,D1,G cell
胰腺疾病英文
Causes
Gallstones:60%( 35–50% in USA)
Alcohol:14% %(60% in USA)
Duodenal juice countercurrent flow: Sphincter of Oddi dysfunction
Trauma
Pancreas circulation disorder
Other factors:
Drug: Azathioprine(硫唑嘌呤) .6-Mercaptopurine(6-巯基嘌呤),
Pancreas divisum(胰分裂),
Microlithiasis
Metabolic cause
Infectious causes, ascaris worms蛔虫,HIV-----
Miscellaneous
急性胰腺炎
Pathology
acute edematous pancreatitis
acute hemorrhagic necrotizing pancreatitis
(acute hemorrhagic pancreatitis, acute necrotizing pancreatitis)
胰腺疾病英文
Pathophysiology
Hypersecretion and obstruction
Self-enzymatic digestion
Enhancement of Vessel permibility Cytokine，infection
Decreased arterial perfusion
Edematous hemorrhagic necrotizing
胰腺疾病英文
Clinical finding
Abdominal pain
Abdominal distention
Nausea and vomiting
Peritonitis
Other:
Respiratory failure, confusion, or coma.
Low-grade to moderate fever
Tachycardia and hypotension and Shock
Mild jaundice,
Pleural effusion.
胰腺疾病英文
胰腺疾病英文
Peritoneal irritation sign （Abdominal tenderness， rebound tenderness and rigidity）
Shifting dullness
Decreased bowel sounds
Cullen’ sign: discoloration of periumbilical area
Grey Turner’ sign:discoloration of flanks