文档介绍：噻托溴铵联合沙美特罗替卡松治疗慢阻肺的疗效分析
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[摘要] 目的 研究對慢阻肺患者实施噻托溴铵与沙美特罗替卡松联合治疗的效果。方法 方便选取该院2017年4月—2018年4月期间收入的84例慢阻肺患者纳入该次实验，根据病历单双号分为单药组42例（噻托溴铵治疗）和联合组42例（沙美特罗替卡松+噻托溴铵治疗），统计并比较两组治疗总有效率、肺功能、不良反应情况。结果 %%，差异有统计学意义（χ2=，P=）;治疗前两组FEV1、FVC以及PEF水平比较，差异无统计学意义（P>）;治疗后两组FEV1、FVC以及PEF水平均升高，但联合组比单药组水平更高，差异有统计学意义（t=、、，P<）;%（3/42）%（2/42）比较，差异无统计学意义（χ2=，P=）。结论 对慢阻肺患者实施噻托溴铵与沙美特罗替卡松联合治疗，可以提高治疗总有效率，利于提升患者肺功能，不会增加药物不良反应，治疗期间较为安全。
[关键词] 慢阻肺;噻托溴铵;沙美特罗替卡松;疗效;安全性
[中图分类号] R563 [文献标识码] A [文章编号] 1674-0742（2020）10（a）-0091-03
Analysis of the Efficacy of Tiotropium Bromide Combined with Salmeterol and Ticasone in the Treatment of Chronic Obstructive Pulmonary Disease
LIU Min， YU Chun-xiao， HUA Jing， ZHANG Jian-hong
Beijing Jingmei Group General Hospital， Beijing， 102300 China
[Abstract] Objective To study the effect of combined treatment of tiotropium bromide and salmeterol on patients with chronic obstructive pulmonary disease. Methods A total of 84 patients with chronic obstructive pulmonary disease who were admitted in the hospital from April 2017 to April 2018 were conveniently selected in this experiment. According to the single and double numbers of the medical records， they were divided into a single-drug group of 42 patients（treated with tiotropium bromide） and a combination group of 42 cases （treatment with salmeterol and tiotropium bromide）， the total effective rate， lung function， and adverse reactions of the two groups were counted and compared. Results The total effective rate of treatment in the combination group was % higher than that of the single-agent group %， the difference was statistically significant （χ2=， P=）; there was no statistically significant difference in the levels of FEV1， FV