文档介绍:Journal of Pharmacological Sciences 140 (2019) 284e290
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Electrophysiological characterization of a small molecule activator on
human ether-a-go-go-related gene (hERG) potassium channel
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Xiuming Dong a, 1, Yani Liu a, , 1, Heling Niu a, Gongxin Wang b, Liying Dong a, b,
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Anruo Zou a, b, KeWei Wang a,
a Department of Pharmacology, Qingdao University School of Pharmacy, 38 Dengzhou Road, Qingdao, 266021, China
b Qing Dao Haiwei Biopharma. , 368 Hedong Road, Qingdao, 266000, China
article info abstract
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Article history: The human ether-a-go-go-related gene (hERG) encodes the K channel that carries the rapid component
Received 26 February 2019 of the delayed rectifier current in the human heart. Reduction of hERG activity induced by g