文档介绍：Journal of Pharmacological Sciences 137 (2018) 274e282
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Full paper
Factor Xa inhibition by rivaroxaban attenuates cardiac remodeling due
to intermittent hypoxia
Hideki Imano a, Ryuji Kato a, Shota Tanikawa a, Fumi Yoshimura a, Atsuo Nomura b,
Yoshio Ijiri a, Takehiro Yamaguchi c, d, Yasukatsu Izumi d, Minoru Yoshiyama c,
*
Tetsuya Hayashi a,
a Department of Cardiovascular Pharmacotherapy and Toxicology, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan
b Department of Pharmacology, Faculty of Medicine, Osaka Medical College, Osaka, Japan
c Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
d Department of Pharmacology, Osaka City University Graduate School of Medicine, Osaka, Japan
article info abstract
Article history: Patients with obstructive sleep apnea (OSA) have a high prevalence of atrial fibrillation (AF). Rivaroxaban,
Received 8 March 2018 a coagu