文档介绍：Characterization of Codon Usage Bias in the Newly
Identified DEV UL53 Gene
Shunchuan Zhang,Anchun Cheng,Mingshu Wang Anchun Cheng,Mingshu Wang
Avian Disease Research Center Key Laboratory of Animal Disease and Human Health of
College of Veterinary Medicine of Sichuan Agricultural Sichuan Province
University College of Veterinary Medicine of Sichuan Agricultural
Ya’an, China University
Ya’an, China
E-mail: ******@vip.
Abstract—Codon usage bias in UL53 gene of DEV was analyzed in the codon usage variation among the genes of Borrelia
this paper, the results indicated that it had strong bias towards to burgdorferi[15].
the synonymous codons with A or T at the third codon position. The
codon usage bias of DEV UL53 gene and 26 reference While factors such as mutational pressure [12,14],
herpesviruses were analyzed by EMBOSS program and RSCU. In translational selection [16-18], and secondary structure of
addition, ic tree indicated DEV was evolutionarily closer proteins [19-21] influenced codon usage in anisms,
to CaHV-2, CaHV-3, MeHV-1. The ENC-GC3S plot revealed that amino acid usage was shown to be governed by
the ic heterogeneity in UL53 gene of herpesviruses was hydrophobicity, aromaticity, cysteine content, and mean
constrained by G+C content at the third codon position. molecular weight [22]. In some other researches