文档介绍：Determination of Substituted Benzenes in Water by
Salting-out Phase Separation Microextraction
Coupled to High Performance Liquid
Chromatography
Jian-ke ZHOU, Kun LONG, Jing PENG
Research Center of Physics and Chemistry Analysis, Hebei University, Key Laboratory of Medical Chemistry and Molecular
Diagnosis, Ministry of Education
Baoding, 071002, China
E-mail: zhoujianke@
Abstract-A trace analytical method of o-chloropheno, spectrometry(LC-MS)[19], capillary isotachophoresis[20], and
chlorobenzene and ethylbenzene in water had been developed by high performance liquid chromatography[21,22] have been used
using salting-out phase separation microextraction coupled to for analysis of substituted benzenes in water samples.
high performance liquid chromatography. A Diamonsil C18 In order to determine trace or ultra-trace substituted
column (5μm, 250× mm .) was used for separation at 30℃ benzenes in water samples, a preconcentration step is often
with detection wavelength at 220 nm; The mobile phase was a necessary prior to analysis. Liquid-liquid extraction (LLE)[11],
mixture of methanol and water (the ratio of volume was 53:47), liquid-liquid-liquid microextraction (LLLME)[18], solid-phase
flow rate was mL/min. The optimal extraction conditions: extraction(SPE)[8], ultrasonic extraction[21], ionic liquid
volume of water was 1