文档介绍：Killing of Escherichia coli by exogenous
hydroxyl radicals

He Hua-gang, Wu Chun-du*, Hou Ke-hui, Wu Chun-du
Zhu Shan-ying, Yi Cheng-wu, Chu Jin-yu Yangzhou College of Environment and Resource
School of Environment Yangzhou, People’s Republic of China
Jiangsu University
Zhenjiang, People’s Republic of China
*E-mail: ******@ujs.

into CO2, H2O and anic salts [3].
Abstract—The effects and mechanisms were
studied on killing of Escherichia coli, a Gram Escherichia coli is a Gram negative
negative bacterium by exogenous hydroxyl radical.
The results showed that, exogenous OH· was bacterium that monly found in the intestine
efficient on killing of E. coli cells. Over 99% of of mammals and birds. Most E. coli strains are
them was killed in mg/L OH· solution. And
exogenous OH· could damage biomolecules of E. harmless, but some strains are harmful to human.
coli. The concentrations and integrities of DNA, The virulent strains, such as O157: H7 or O111:
RNA and intracellular protein decreased with the
increasing of the concentration of OH·, and the B4, can cause serious food poisoning, serious
degree of decreasing of intracellular soluble illness or death [4]. As a model, E. coli was used
protein concentration was higher than that of DNA
or RNA. This indicated that protein is the major in this study. We attempt to analyze the effects o