文档介绍：多奈哌齐联合丁苯酞治疗血管性认知功能障碍的临床观察摘要: 目的: 观察多奈哌齐联合丁苯酞软胶囊对血管性认知功能障碍(VCI) 患者的治疗作用。方法: VCI 患者 60 例随机分为观察组和对照组各 30 例,观察组给予丁苯酞软胶囊与多奈哌齐联合治疗,多对照组仅给予多奈哌齐。 2 组患者在治疗前和治疗 8 周后分别采用简易智力状态量表( MMSE )、日常生活活动能力量表( ADL ) 进行评分。结果: 治疗后两组 ADL 积分降低,MMSE 积分提高, 观察组优于对照组(P<) 。结论: 多奈哌齐联合丁苯酞软胶囊对血管性认知障碍者的认知功能有较好的改善作用。关键词: 血管性认知功能障碍;多奈哌齐;丁苯酞 Abstract:Objective To evaluate the clinical efficacy bined use of donepezil and butylphthalide soft capsules on the treatment of vascular cognitive 60 Patients with vascular cognitive impairment were randomly divided into the treatment group and the control group,each had 30 patients. Butylphthalide soft capsules were used for the treatment group. The control group only used the donepezil. Beofre and after the 8 weeks trealment ,MMSE scale and ADL scale was used to assess the therapeutic effect. Results After treatment the ADL scores decreased and the MMSE scores increased in two groups. The MMSE scores and ADL scores in the treatment group were superior to that in control group(P<). Conclusion For the patients with vascular cognitive impairment,,bined use of donepezil and butylphthalide soft capsules can greatly improve the patient ’s congnitive function. Keywords: Vascular cognitive impairment; Donepezil; Butylphthalide soft capsules 血管性认知功能障碍( VCI ) 是指由脑血管病危险因素( 高血压、糖尿病、高血脂等), 明显( 脑梗死和脑出血等) 或不明显( 白质疏松和慢性脑缺血等) 脑血管病引起的从轻度认知障碍到痴呆的一大类综合征。血管性痴呆(vascular