文档介绍：奇星四方胃片,法莫替丁及两者合用对急性胃黏膜损伤的抑制作用
[摘要] 目的观察法莫替丁(西药), 奇星四方胃片(中成药)及两者合用对急性胃黏膜损伤的抑制作用研究两者合用之疗效是否优于单一用药的疗效。方法将大鼠随机分成生理盐水组、法莫替丁组、奇星四方胃片组、两者合用组、病理模型组,利用乙醇制得胃黏膜损伤模型,观察胃黏膜出血带的多少,采用Kitagawa积分方法记录结果。结果法莫替丁药效最强(%),奇星四方胃片次之(%),两者混用效果最差(%)。结论法莫替丁、奇星四方胃片及两者联用对胃黏膜损伤均有抑制作用,疗效各异。
[关键词] 奇星四方胃片法莫替丁急性胃黏膜损伤
The inhibitory effect of SiFangWeiPian 、Amotidine Tablets and bination of the two on acute gastromucous injury FEI Hui, WANG Bufei, WU Yuankai, ZHAO 1,Grade 00,Department of Clinic Meicine,Zhongshan University,Guangzhou 510089,China。 Tutor:WANG Tinghuai。 Department of Physiology, Zhongshan University,Guangzhou 510089,China
[Abstract] Objective To observe the inhibitory effect of SiFangWeiPian,Amotidine Tablets on acute gastromucous injury,and to investigate whether bination of the two has better effect. Methods 40 white rats were randomly divided into 5 groups-8 rats per group,which was respectively treated by NS, SiFangWeiPian,Amotidine Tablets and bination of the two drugs.(ig). Secondly, to make the pathology model by % the length of the gastromucous hemorrhage band according to the Kitagawa integral method. Rusults Amotidine has the best effect(inhibitory %),SiFangWeiPian is at the second place(inhibitory % ),but bination has the least effect(%) . Conclusions SiFangWEiPian Amotidi