文档介绍：痛风治疗指南
痛风治疗指南
痛风治疗指南
痛风治疗指南
痛风治疗指南
痛风治疗指南
欧洲抗风湿联盟(EULAR)对痛风治疗的12项建议
1、 Optimal treatment of gout requires breatment for an acute attack、 Strength of recommendation: 80 (95% CI, 73 to 87)
。推荐力度:80(95%的可信区间73-87)
7、 Urate lowering therapy is indicated in patients with recurrent acute attacks, arthropathy, tophi, or radiographic changes of gout、 Strength of recommendation: 97 (95% CI, 95 to 99)
、关节病、痛风石或有放射线改变的痛风患者应行降尿酸治疗。推荐力度:97(95%的可信区间95-99)
8、 The therapeutic goal of urate lowering therapy is to promote crystal dissolution and prevent crystal formation、 This is achieved by maintaining the serum uric acid below the saturation point for monosodium urate ( 360 µmol/l or 6 mg/dl)、 Strength of recommendation: 91 (95% CI, 86 to 96)
,这就需要使血尿酸水平低于尿酸单钠的饱与点( 360 µmol/l 或 6 mg/dl)、 推荐力度:91(95%的可信区间86-96)
9、 Allopurinol is an appropriate long term urate lowering therapy、 It should be started at a low dose (100 mg daily) and increased by 100 mg every two to four weeks if required、 The dose must be adjusted in patients with renal impairment、 If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash)、 Strength of recommendation: 91 (95% CI, 88 to 95)
。应以低剂量开始(100mg/d),如有需要,则每2-