文档介绍：检验医学 2021 年 5 月第 36 卷第 5 期 Laboratory Medicine，May 2021，Vol. 36，No. 5 ·471·
of Clinical Laboratory，Zhongshan Hospital，Fudan University（Xiamen Branch），Xiamen 361015，Fujian，China）
Abstract：Objective To evaluate the performance of immunosuppressive assay for mitochondrial aspartate
aminotransferase（m-AST），and to investigate the changes of serum aspartate aminotransferase（AST），
m-AST and m-AST/AST in patients with coronary heart disease（CHD） and acute myocardial infarction（AMI）.
Methods The determination performance（precision，accuracy，linear range，reference interval，maximum
dilution ratio）of immunosuppressive assay for m-AST was evaluated. Totally，44 patients with CHD undergoing
drug-eluting stent implantation and 44 emergency patients with AMI undergoing percutaneous coronary intervention
（PCI） were enrolled. Preoperative and postoperative AST and m-AST levels were determined，the ratio of m-AST/
AST was calculated，and their correlations with Gensini score were analyzed. Results The precision，accuracy，
linear range and reference interval of immunosuppressive assay for m-AST were all verified，which met the clinical
基金项目：国家自然科学基金面上项目（81772263）；国家自然科学基金面上项目（81972000）；国家自然科学基金青年项目（81902139）；
2019厦门市医疗卫生重点项目