文档介绍：中华中医药学刊
第 32 卷第 1 期 Vol. 32 No. 1
2 0 1 4 年 1 月 CHINESE ARCHIVES OF TRADITIONAL CHINESE MEDICINE Jan. 2 0 1 4
DOI 10. 13193 /j. issn. 1673-7717. 2014. 01. 026
从基因角度对卵巢早衰病因及治疗的研究
郭菲,刘丹卓,赵新广
,
湖南中医药大学湖南长沙 410007
摘要卵巢早衰发病原因复杂,治疗效果亦不理想,近年研究显示,染色体上某些基因出现异常可能与卵巢
早衰的发生密切相关,相关基因的发现,为基因治疗提供了依据,不仅可筛查相关基因来预测妇女是否会发生过
早绝经,使其能及时选择最佳生育时机,还可采用一些措施对其表达进行调控,以达到治疗此病的目的。尽管基
因角度的卵巢早衰研究并不完善,但寻找相关基因并进行治疗的研究前景看好,它为从基因角度完整地阐明卵巢
早衰的病因,并研制出基因调控药物提供了可能性,有希望从根本上解决卵衰早衰问题。
关键词卵巢早衰基因病因治疗中医药
中图分类号 R271. 1 文献标志码 A 文章编号 1673-7717 2014 01-0081-03
Research on ic Pathogenesis and Treatment of Premature Ovarian Failure
, ,
GUO Fei LIU Danzhuo ZHAO Xinguang
, , ,
Hunan University of Traditional Chinese medicine Changsha 410007 Hunan China
,
Abstract The pathogenesis of premature ovarian failure plex and the treatment effect is unsatisfactory. Recent
research has shown that some abnormal genes may be closely related with premature ovarian failure. The research result of
,
related genes provides the basis for gene treatment which can not only predict whether women will get premature meno-
,
pause by screening related genes so that they can choose the best birth time but also take measures to regulate the expres-
,
sion of the genes to cure this disease. Although the study on ic premature ovarian failure is not perfect the expecta-
tion of searching related