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牙体牙髓牙周病学杂志(Chin J Conserv Dent) 2006, 16 (4) · 229·
佳洁士含三***生牙膏和佳洁士防蛀修复牙膏
抑菌作用的比较研究
韩静, 杨圣辉
(首都医科大学附属北京口腔医院研究所,北京 100050)
[摘要] 目的:比较佳洁士含三***生牙膏和佳洁士防蛀修复牙膏的抑菌效果及作用时间。方法:选
用变形链球菌、牙龈卟啉单胞菌等为实验菌株, 用微孔板微量液体稀释法对两种牙膏进行细菌敏感实验,比较
二者对不同菌株的最低抑菌浓度(M IC) ;并选择 22名受试者,在晚间和清晨分别使用两种牙膏按指定方法刷
牙后,观察两种牙膏抑菌作用的持续时间。结果: ①含三***生牙膏对 5种菌的抑菌浓度均低于防蛀修复牙膏。
②22名受试者使用含三***生牙膏刷牙后,清晨抑菌作用保持率为 81. 8% ,日间检出率下降,为 40. 9% ;防蛀修
复组抑菌作用保持率为 0。统计学差异具有显著性意义。结论:佳洁士含三***生牙膏抑菌作用较强,使用后能
持续发挥抑菌作用,其夜间抑菌作用优于日间。
[关键词] 三***生; 牙膏; 抑菌
[中图分类号] R780. 1 [文献标识码] A [文章编号]1005 - 2593 (2006) 04 - 0229 - 03
[牙体牙髓牙周病学杂志, 2006, 16 (4) : 229 ]
Comparison of the anti - bacterial efficacy of a new kind
of crest toothpaste conta in ing triclosan
to crest anti - cavity toothpaste
HAN J ing, YANG Sheng - Hui
(B eijing D ental Institution, Affiliated Hospital, CapitalM edical U niversity, B eijing 100050, China)
[ Abstract] A IM : pare the Anti - bacterial efficacy and the lasting effect of the new kind of Crest
Toothpaste ( containing triclosan) and Crest Anti - Cavity Toothpaste. M ETHOD S: The m inimal inhibitory concentra
tions(M ICs) of the new kind of Crest Toothpaste and Crest Anti - Cavity Toothpaste to S us m utans and
P. gingivalis pared by m icrobial p late assay technique. The lasting effect of the two toothpastes used before
sleep ing and after the next breakfast abiding by regulating method w