文档介绍：四川生理科学杂志 2021, 43(7) 1113
bservation group and control group (n=44) according to random number table method.
The control group was treated with oral estradiol valerate tablets, and the observation group was treated with estradiol
tablets/estradiol didrogesterone tablets. After 21 days of treatment, menstrual duration and menstrual volume were
recorded. Endometrial thickness was measured by ultrasound before and after treatment. The serum levels of Matrix
metallo-Proteinase-9 (MMP-9), TGF-β1 (Transformating growth factor -β1) and sex hormones, including FSH (Follicle
stimulating hormone), Estradiol (E2) and Luteinizing hormone, were determined by ELISA and radioimmune-
oturbidimetry. The recurrence rate was observed at 6 m follow-up. Results: After treatment, the duration of
menstruation in the observation group was longer than that in the control group, the menstrual volume was higher than
that in the control group, the endometrial thickness was thicker than that in the control group, the serum levels of E2
and MMP-9 were higher than that in the control group, the levels of FSH, LH and TGF-β1 were lower than that in the
control group, and the recurrence rate was lower than that in the control