文档介绍：- 312 - Drug Evaluation Research August 2010
决明子化学成分及药理作用研究进展
刘斌 1,巩鸿霞 2,肖学凤 1 *,叶贵福 1
1 天津中医药大学中药学院,天津 300193;
2 天津市南开医院眼科,天津 300100
摘要决明子含蒽醌类、黄酮类及其他多种成分,具有降血脂、降血压、清肝明目及抑菌消炎之功效。对决明子化学成分
及其药理作用进行综述,为决明子及其提取物的质量监控和开发利用提供参考依据。
关键词决明子;化学成分;指纹图谱;药理作用
中图分类号: 文献标志码:A 文章编号:1674–6376(2010)04–0312–04
Advances in studies on chemical constituents of Cassia Semen and their
pharmacological activities
LIU Bin1, GONG Hong-xia2, XIAO Xue-feng1, YE Gui-fu1
1 Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;
2 Department of Ophthalmology, Tianjin Nankai Hospital, Tianjin 300100, China
Abstract In Cassia Semen there are anthraquinone constituents and some others, which have the functions of lowering the blood
presure and reducing fat, removing intensive heat from the liver and improving acuity of sight, as well as the bacteriostatic
and anti-inflammation. In this paper, the constituents and pharmacological effects of Cassia Semen are reviewed, the
reference basis on the quality control and the utilization of Cassia Semen and its extracts have been provided.
Key words Cassia Semen; constituents; pharmacological effects

决明子是豆科植物决明 Cassia obtusifolia
小决明 C. tora 。决明子是我国历(chrysophanol)、大黄素甲醚(physcion)、美决明子
史悠久的药用植物,最早《神农本草经》将决明子素(obtusifolin)、黄决明素(chryso-obtusin)、决明
列为上品,称之“能治诸眼疾,