文档介绍：NEPHROLOGY 2000; 5, 209–213
Review
Management of m Table1).2,3 by a spontaneous remitting and relapsing course in many
The depth of the search for secondary causes varies by Complete remission can be seen in as many
both the age of the patient and his geography. In Africa, as 35% of the subjects of long-term (> 10 years) studies,
for instance, an infectious cause such as malaria is with up to 50% having at least one relapse. A com-
common, and in Asia, hepatitis B is a frequent aetiologi- plete remission and a reduction in the relapse rate is
cal agent. The issue of age relates to the association of more common in female patients and those with per-
malignancy with membranous This asso- sistent subnephrotic-range proteinuria. In contrast,
ciation is stronger in the age group above 55 years. In the male gender, age > 50 years, high levels of protein-
patients < 55 years, a search for an occult malignancy in uria (> 5 g/d), abnormal renal function at presentation
the absence of any signs or symptoms should be limited, and tubular interstitial disease on biopsy have all been
but investigations should probably include a chest associated with a poor prognosis.
radiograph, a stool examination for occult blood, mam-
mography in women and, perhaps, a prostate-specific
antigen t