文档介绍:临床医学 临床医学研究与实践 2022 年 5 月第 7 卷第 14 期
丁苯酞软胶囊联合多巴丝肼vodopa and benserazide hydrochloride tablets) by random number
table method. The therapeutic effects of the two groups were compared. Results The total effective rate of treatment in the
observation group was higher than that in the control group (P<). After treatment, the scores of HAMA, PQSI and
PDQ-39 decreased, while the scores of MoCA and SF-36 increased in the two groups, and those in the observation group
were better than the control group (P<). After treatment, the levels of NT-3 and BDNF in both groups significantly
increased, and those in the observation group were higher than the control group (P<). After treatment, the levels of
PARK7 and MDA in both groups decreased, and the level of SOD increased, and those in the observation group were better
than the control group (P <). Conclusion Butylphthalide soft capsules combined with levodopa and benserazide
hydrochloride tablets can improve motor and non-motor symptoms of PD patients, improve neurological function, reduce
oxidative stress response and improve the quality of life of PD patients.
KEYWORDS: butylphthalide soft capsules; levodopa and benserazide hydrochloride tablets; Parkinson's disease
帕金森(PD)是以静止性震颤、运动迟缓及颈强直为