文档介绍：临床医学论文-某农村人群甲、乙、丙、戊和庚型肝炎病毒感染的现况研究
【摘要】目的了解某农村人群甲、乙、丙、戊和庚型肝炎病毒的感染状况及其流行特点。方法应用酶联免疫试验(EIA)检测血清抗-HAV、HBsAg、抗-HBs、抗-HBc、抗-HCV、抗-HEV和抗-HGV,并对抗-HGV阳性者应用套式逆转录聚合酶链反应法(RT-nPCR)检测HGV RNA。结果该人群抗-HAV、抗-HCV、抗-HEV和抗-%、%、%%,%,%。HAV以5岁以下儿童感染率最低(%),%的儿童已感染HAV。HBsAg阳性率呈现两个高峰,分别在5~9岁和40~49岁年龄组;%,然后随年龄增长而上升。HCV感染主要集中在20~49岁年龄组(%)。各型肝炎病毒男女感染率无明显差异。献浆次数、年限与HCV、HEV、HGV感染呈正相关。HBsAg、抗-HBc、抗-HCV呈现家庭聚集性,但仅HBsAg呈现母亲与子女相关。抗-HCV阳性者中ALT异常率(%)显著高于抗-HCV阴性者(%,P<)。结论该人群甲、乙、丙、戊和庚型肝炎病毒感染具有不同的流行病学特点;献血浆是该人群HCV、HEV和HGV感染的主要危险因素;抗-HCV阳性者多伴有肝损害。
A cross-sectional study on HAV,HBV,HCV,HEV and HGV infection in a rural population
 
【Abstract】 Objective To study the epidemiological characteristics of HAV,HBV,HCV,HEV and HGV infections in a rural population. Methods Enzyme immunoassays were used for detection of anti-HAV,HBsAg,anti-HBs,anti-HCV,anti-HEV and anti-HGV. Anti-HGV positive sera were further tested for HGV RNA using a reverse transcription nested PCR. Results The prevalence rates of anti-HAV,HBsAg,anti-HCV,anti-HEV,anti-HGV in the studied population were %,%,%,% and %,respectively. The total infection rate of HBV was %. The HAV infection rate of children below 5 was the lowest (%) pared with other age groups.&n bsp;% of children at 10 years old had already been infected with HAV. The