文档介绍：1 不同胎龄早产儿血脂生化指标的临床意义作者: 尹力扬, 王红兵, 徐丽, 刘淑华, 董雪萍, 梁世磊,张大葵,李文斌【摘要】目的通过测定不同胎龄早产儿血脂生化指标的变化, 探讨其作为评价早产儿成熟度、营养状况及营养支持指标的临床意义。方法早产儿组30 例在入院后 12h内(出生后 24 h) 采集股静脉血 2 ml ,采血前 2h 未喂养及输液。足月儿组 30 例在胎儿娩出、清理呼吸道后即刻采脐带血 2 ml。测定血清总胆固醇(TC) 、甘油三酯(TG) 、高密度脂蛋白胆固醇(HDL-C) 、低密度脂蛋白胆固醇(LDL-C) 、载脂蛋白 A1(ApoA1) 、载脂蛋白 B(ApoB) 等生化指标。结果早产儿组血清 TC 、 TG 、 HDL-C 、 LDL-C 、 ApoA1 、 ApoB 水平均低于足月儿组,2 组之间差异具有统计学意义() 。 28~ 31周的早产儿组血清 TC 、 TG 、 HDL-C 、 LDL-C 、 ApoA1 、 Apo B 水平均低于 32~ 36 周的早产儿组, 2 组之间差异具有统计学意义() 。结论血脂生化指标可作为评价早产儿成熟度及营养状况的依据。检测血脂水平变化, 对临床合理营养支持具有指导意义。 2 【关键词】早产儿; 血脂; 成熟度; 营养状况; 营养支持 Abstract: Objective By measuring the biochemical changes in blood lipids in premature infants of different gestational age, to explore thEir clinical significance as biochemical indexes to evaluate the maturity, nutritional status and nutritional support in premature infants. Methods 30 premature infants admitted to hospital were designated as the premature group. Blood collection of2 ml was performed from the femoral vEIn within 12 hours after admission (24 hours after birth). 2 hours before blood collection, the premature infants received no transfusion or feeding. 30 neonates of term delivery underwent blood collection of2 ml from the umbilical cord immediately after delivery and airway clearance. Determinations were conducted on the biochemical indicators including serum total cholesterol (TC), triglyceride (TG),