文档介绍:1 慢性肾衰者同型半胱氨酸与心衰指数关系研究作者:余海峰陈军斌李招云邓晓燕李春胜【关键词】慢性肾衰【摘要】目的探讨慢性肾衰患者同型半胱氨酸( Hcy )与心衰指数( HFI )间相关关系。方法 90 例肾衰及 58 例肾功能正常者采用荧光偏振免疫法测定 Hcy 。 HFI 按 Boston 心力衰竭标准评分。结果非心衰组、可疑心衰组、心衰组 Hc y 分别为( ± , ± , ± )μ mol/L ,三组间差异显著。通过偏相关分析及逐步回归分析,均提示 HF I 与 Hcy 关系最密切。结论 Hcy 与 HFI 呈显著正相关,是预测早期心力衰竭的一个有效指标。关键词慢性肾衰同型半胱氨酸心衰指数【 Abstract 】 Objective To investigate the correlation between homocystEine ( Hcy ) and heart failure index ( HFI ) in patients with chronic renal failure ( CRF ) .Methods Hcy was measured 2 in90patients with CRF , and58patients with normal renalfunction With fluorescence polarization immunoassay , scored with heart failure standard of to the score , 30patients were distributed to heart failure group ( HF group , score was8or over8 ), 19patients to heart suspicious failure group ( HSF group , score between4and7 ), 99patients to heart non-failure group ( HNF group , score was3or smaller than3 ) .Results The plasma lever of Hcy in HF group was higher than that in HSF group ( ± μ mol/L ± μ mol/L , ) .The plasma lever of Hcy in HSF group was higher than that in HNF group ( ± μ mol/L ± μ mol/L , ) .With partial correlation anal ˉ ysis and stepping regression analysis , the plasma lever of Hcy had significant positive correlation with HFI ( r= , ) .Conclusion Plasma Hcy may be mo