文档介绍：1 抗精神病药物对女性精神病患者血清催乳素的影响【摘要】目的探讨抗精神病药物对女性精神分裂症患者血清催乳素的影响。方法对 80 例女性精神分裂症患者服用不同抗精神病药物治疗前后的血清催乳素水平进行测评分析。结果不同药物治疗后的血清催乳素平均水平各不相同, 舒必利、奋乃静、***哌啶醇、***治疗后血清催乳素水平均显著升高(P< 或 ); ***氮平对催乳素水平影响不明显。各类药物剂量与血清催乳素之间的直线回归分析显示,在引起血清催乳素明显升高的药物中, 剂量和血清催乳素水平呈正相关。结论长期应用抗精神病药物治疗可影响患者的血清催乳素水平, 临床医生应充分注意,发现血清催乳素水平异常者,应及时的给予处理。【关键词】精神分裂症; 女性; 抗精神病药; 高催乳素血症 Effects of antipsychotics on serum prolactin of female psychotics 2 【 Abstract 】 Objective To explore the effects of antipsychotics on serum prolactin of female psychotics. Methods Serum prolactin levels were meaured and analyzed in 80 schizophrenics taking different antipsychotics before and after Serum prolactin levels of different antipsychotics were different, posttreatment serum prolactin levels of sulpiride,perphenazine, aloperidin and risperidone significantly advanced( or ); clozapine had no notable effect on prolactin level. Linear regression analyses between drug doses and serum prolactin showed that among drugs causing obvious advancement, doses were positively related to serum prolactin Long 拟 term antipsychotics ’ treatment can influence serum prolactin levels, clinicians should fully pay attention to and promptly give treatment once discovering advancement of serum prolatin. 【 Keywords 】 Schizophrenia; female; antipsychotics; hyperprolactinemia 抗精神病药物( APD ) 可引起精神分裂症患者内分泌、代谢异常, 不仅给患者带来