文档介绍：1 静脉注射丙种球蛋白治疗川崎病的疗效分析作者:胡女元余永芳黄健瑜【关键词】静脉注射摘要: 目的: 探讨不同用法静脉输注丙种球蛋白( IVIG ) 治疗小儿川崎病的临床疗效。方法:对 93 例川崎病( KD ) 患儿采用两种不同治疗方案: A 组为 IVIG ― 1g/kg 单次静脉输注;B 组为 IVIG , 连用 4~ 5d。对比两组治疗后冠状动脉病变(CAD) 发生率和急性期临床症状消失时间。结果: 川崎病发病 10d内 IVIG 1g/k g和 . d连用4~5d 均能有效预防 CAD 的发生; 急性期临床症状缓解方面: IVIG 1g/k g 组明显优于 IVIG 组,差异有显著性。结论: IVIG 1g/kg 单次静脉输注为治疗小儿川崎病经济方便和有效的方法。关键词:粘膜皮肤淋巴结综合征;免疫球蛋白类;静脉内;冠状动脉病变 2 Analysis of Treating Kawasaki Disease with Intravenous Immunoglobulin Abstract : Objective : To explore the clinical effect of treating Kawasaki disease with different IVIG dosage. Method : 93 patients were divided into 2 groups with different dosage for the treatment: the dosage of Group A was IVIG 1g/kg only once, the dosage of Group B was IVIG / everyday, lasting 4~5 days. Result : CAD was effectively prevented by Either 1g/kg or / (lasting 4~5 days) of IVIG within 10 days after the onset of the illness . On the remission of acute phrase symptoms, the regimen of 1g/kg IVIG was obviously better than the one of / IVIG. Conclusion : 1g/kg IVIG is an effective and economic dosage for the treatment of Kawasaki disease. Key words: Mucocutoneous lymph node syndrome; Immunoglobulins;Intravenous; Coronary artery disease 198 4年 Furusho K 首先提出在川崎病患者的急性期应用大剂量静脉丙种球蛋白( IVIG ) 能减少冠状动脉瘤( CAA ) 的发生[ 1]。目前国内外围绕小儿川崎病 IVIG 优选方法 3 的研究尚未取得一致的结论。本文分析了 93 例川崎病患儿应用两种不同治疗方案在预防冠状动脉病