文档介绍:2
心理干预及癌痛规范化治疗对癌症患者T细胞表面PD―1、Tim―3的影响
[Abstract] Objective To study the effect of mental intervention and standardiz2
心理干预及癌痛规范化治疗对癌症患者T细胞表面PD―1、Tim―3的影响
[Abstract] Objective To study the effect of mental intervention and standardized treatment of cancer pains on the T cell surface PD-1 and Tim-3 of cancer patients. Methods Convenient selection 80 cases of cancer pain patients treated with standardized analgesia in our hospital from June 2015 to November 2016 were selected and randomly divided into two groups with 40 cases in each, both groups received the standardized treatment of cancer pains, the control group adopted the routine nursing, while the research group adopted the mental intervention of psychologists, and the pain degree before and after treatment of the two groups was evaluated by NRS, and the peripheral blood CD4+T cell and expression of CD8+T cell surface PD-1 and Tim-3 before and after treatment of the two groups was tested by the flow cytometer. Results The NRS score in the research group and in the control group before treatment was respectively (±)points and (±)points and (± )points and (±)points after treatment, and the NRS score in the research group was obviously lower than that in the control group after treatment, and the difference had statistical significance(P<), after treatment, the expression level of CD