文档介绍：Myocardial Viability
Clinical– angina
PET
MRI
Thallium
Dobutamine Echo
Guludec DL, Eur J Nucl Med Mol Imaging (2008) 35:1709–1724
Cardiac Perfusion and Viability Study by PET/CT
75 year old male
Scan protocol: low dose CT for attenuation correction
PET 740 MBq NH3, 10 minute scan, 370 MBq FDG, 10 minute scan
Data Courtesy of University of Michigan
0
12
24
36
48
60
Time (months)
Medical
CABG
p =
Survival Probability
With PET Mismatch
Without PET Mismatch
0
12
24
36
48
60
Medical
CABG
NS
Time (months)
Survival by Viability and Treatment
Di Carli et al, J Thor Cardiovasc Surg 1998; 116: 997
93 Patients with Ischemic Cardiomyopathy and severely depressed left ventricular function
FDG IMAGING IN LV ANEURYSMS
Zhang X et al J Nucl Med 2008; 49:1288–1298
70 pts with LV aneurysm
yrs FU
Surgery for viability improved EF and survival (p .0001)
Medical therapy with vi