【医学英文文献】Temporal lobe necrosis a dwindling entity in a patient with nasopharyngeal cancer after radiation therapy.pdf

文档介绍：Dassarath et al. Head & Neck Oncology 2011, 3:8
tent/3/1/8
CASE REPORT Open Access
Temporal lobe necrosis: a dwindling entity in a
patient with nasopharyngeal cancer after
radiation therapy
Meera Dassarath1,2†, Zhongyuan Yin1†, Jing Chen1, Hongli Liu1, Kunyu Yang1*, Gang Wu1
Abstract
Introduction: Our objective was to report a case of misdiagnosed temporal lobe necrosis (TLN) in a patient with
nasopharyngeal cancer (NPC) after radiation therapy.
Case Presentation: We report a case of a 45 years old Chinese woman who developed moderate to severe
headache and dizziness 1 year after 2D radiation therapy for NPC. Subsequent MRI scanning revealed a big
enhancing mass in the right temporal lobe. The initial diagnosis was metastatic or intracranial extension of NPC, or
a primary intracranial malignancy. She was referred to the neurosurgery department where a maximal surgical
resection of the lesion was performed. A diagnosis of TLN was made according to the final histology.
Conclusion: TLN still matters in the IMRT era. The diagnostic quagmire of TLN lies in its close resemblance to
neoplasm on clinical presentation and imaging. Reviewing the patient’s treatment plan to scrutinize the dose to
the temporal lobes is an important prerequisite for diagnosis.
Introduction decline of plication has been observed since the
Worldwide, nasopharyngeal cancer (NPC)