文档介绍：ChapterChapter 55 RespirationRespiration
DepartmentDepartment ofof PhysiologyPhysiology
WestWest ChinaChina SchoolSchool ofof PreclinicalPreclinical andand
ForensicForensic Medicine,Medicine, SichuanSichuan UniversityUniversity
Concept of Respiration
the process of gas exchange between the
organism and the atmosphere
Significance of Respiration
To provide O2 to the tissues and remove CO 2
from the body
Process of Respiration
External environment
O2
ExternalExternal Conducting Pulmonary
ventilation(1)
respirationrespiration airways
Alveoli Gas exchange(2)
CO
Pulmonary PO2 < 40 2 PO2 = 100 Pulmonary
Pulmonary capillaries
artery PCO2 > 45 PCO2 = 40 vein
Gas transport in the
Right blood (3) Left
Veins Aorta
Systemic capillaries O2
InternalInternal
respiration Metabolizing tissues Gas exchange(4)
respiration CO 2
Cellular respiration (5)
Topics in This Chapter
Pulmonary Ventilation
Respiratory Gases Exchange
Gas Transport in the Blood
Regulation of Respiration
SectionSection 11 PulmonaryPulmonary VentilationVentilation
(English textbook P. 432-443)
PulmonaryPulmonary VentilationVentilation
the process of gas exchange between the
lung and the atmosphere
PrinciplesPrinciples ofof PulmonaryPulmonary VentilationVentilation
¢¢ DrivingDriving forceforce
Direct force ——
Pressure gradient
(Alveolar P.
-Atmospheric P.)
Motive force ——
Respiratory movement
Elastic resistance
¢¢ ResistanceResistance
Non-elastic resistance
ĉĉĉĉĉĉ.. RespiratoryRespiratory movementmovement ————
motivemotive forceforce ofof pulmonarypulmonary ventilationventilation
RespiratoryRespiratory movement:movement:
rhythmic expansion
and contraction of
thorax caused by
movement of
respiratory muscles.
. RespiratoryRespiratory musclesmuscles
diaphragm (most important )
Muscles of
external intercostal muscle
inspiration
accessory muscles: scalene,
sternocleidomastoid
Muscles of internal