文档介绍：清咽排毒颗粒的药效学研究【摘要】目的研究清咽排毒颗粒在解热、镇痛、抗炎、止咳、祛痰、体外抗菌、体外抗病毒等方面的作用,为其临床用于风热型急性咽炎提供了实验依据。方法选用2,4二硝基苯酚致大鼠发热法、热板法、二甲苯所致小鼠耳廓肿胀法、氨水引咳法、小鼠酚红排泄法、最低抑菌浓度法和鸡胚内抗病毒法。结果清咽排毒颗粒对2,4二硝基苯酚所致大鼠发热有显著的解热作用;对热板法引起的疼痛具有明显的镇痛作用;对二甲苯所致小鼠耳肿胀有明显的抑制作用;能明显抑制氨水引起的小鼠咳嗽,促进小鼠气管酚红排泄;对金黄色葡萄球菌、乙型溶血性链球菌、肺炎克雷伯氏菌、大肠杆菌、甲型流感病毒H1N1有一定抑制作用。结论清咽排毒颗粒具有解热、镇痛、抗炎、止咳、祛痰、体外抗菌、体外抗病毒等方面的作用。【关键词】清咽排毒颗粒;解热;镇痛;抗炎;止咳;祛痰;抗菌;抗病毒Abstract:ObjectiveTostudythepharmacodynamicactionsofQingyanPaiduGranuleaboutantipyretic,analgesic,anti-inflamatory,antitussive,expectorant,bacteriostasis,,4--inflammationactionbyusingauricleswellinginmicecausedbybimethylbenzeneandantitussiveeffectbyusingcough-modelinmicecausedbyammoniawereobservedandthequantityofphenolredsecretedfromthemice',analgesicaction,anti-inflammationyaction,antitussiveaction,andexpectorantaction;i,beta-i,us,Escherichiacoli,,analgesia,anti-inflammation,antitussive,expectorant,bacteriostasis,:QingyanPaiduGranule;Antipyretic;Analgesia;Anti-inflammation;Antitussive;Expectorant;Bac