文档介绍：183株嗜麦芽窄食单胞菌感染的临床及抗菌药物使用分析
薛洪源1,侯天文2(,河北石家庄 050082;2. 白求恩医院检验科,河北石家庄 050082)
目的:分析和总结183株嗜麦芽窄食单胞菌的感染情况和对抗菌药的耐药情况,为临床预防和治疗该菌引起的感染提供依据。方法:对临床标本中分离的183株嗜麦芽窄食单胞菌进行细菌鉴定和药敏试验,复习有关临床资料,分析发病的危险因素。结果: 183株嗜麦芽窄食单胞菌的检出标本以痰为主,%;居检出临床科室前4位的依次为呼吸科(%)、老干部科(%)、ICU病房(%)、肿瘤科(%);高龄、侵入性诊疗操作、使用广谱抗菌药为嗜麦芽窄食单胞菌感染的危险因素,%、%、100%;183株对常用抗菌素耐药,敏感率超过50%的抗菌药依次为复方磺胺甲噁唑(%)、头孢哌酮钠/舒巴坦(%)、哌拉西林/他唑巴坦(%)、环丙沙星(%)。结论:嗜麦芽窄食单胞菌感染多发生在有各种基础疾病、免疫力低的患者,该菌耐药现象严重,治疗应根据药敏试验结果合理选用抗菌药。
[关键词] 细菌,嗜麦芽窄食单胞菌,感染,抗生素
Analysis of clinical characteristics and drug sensitivity tests of 183 strains of infection by stenotrophomonas maltophilia
Xuehongyuan1,Houtianwen2 (. of Pharmacology;. of Clinical Laboratory, Bethune International Peace Hospital, Shijiazhuang 050082, China)
[Abstract] Objective: To analyse the situation of epidemic and antibiotic resistance of Stenotrophomonasmaltophilia in order to provide basis for the prevention and treatment of the infection indused by the bacterium. Methods: 183 strains of Stenotrophomonasmaltophilia from clinical isolates were identified and their susceptibility was tested. Clinical data were reviewed, and risk factors were analysized. Results: Most of 183 strains were isolated from sputum(%). 183strains were mainly isolated from department of respiratory medicine(%), ICU(%), department of cadre(%)