文档介绍：393例儿童药品不良反应分析
【摘要】目的为儿童临床安全用药提供依据,促进儿童合理用药。方法采用回顾性调查方法对我院2009~2011年度上报的393例ADR报表,按照患者年龄、性别、给药途径、ADR累及器官、新的和严重的ADR、报告人职业等进行统计、分析。结果 1~2岁发生ADR的例数较多,有102例;静脉给药方式引发的ADR数量最多,有385例;β—内酰胺类引起的ADR居多,有338例;ADR的临床表现以皮肤、粘膜及附件的损害最多,有377例。结论儿童药品不良反应的发生率高,尤其是抗生素的过度及不规范使用引起的ADR严重威胁儿童的健康,因此应加强儿童不合理用药的监管,建立积极主动的儿童药品不良反应监测体系。
【关键词】儿童药品不良反应监测分析
ABSTRACT OBJECTIVE:To provide the basis of rational and safety using drugs for children. METHODS: 393 cases of ADR reports in our hospital from 2009 to 2011 was analyized by a retrospective survey method,according to patient’s age,gender,route of administration,ans and systems involved in ADR, new and serious ADR,the reporting person occupation. RESULTS: Childrens from 1 to 2 years occurred more ADR,there were 102 cases. Intravenous drug delivery caused the largest number of ADR, there were 385 cases . β-lactam antibiotics casued the majority of ADR, there were 338 cases . organs and systems involved in ADR were skin and its appendants, there were 377 cases. CONCLUSION: The high incide
nce of ADR of children ,especially casused by the excessive and non-standard use of antibiotics seriously threat to the health of children . So a more proactive monitoring system of ADR for children should be set up to strengthen the supervision of irrational drug use.
【KEY WORDS】 Children Adverse drug reactions Monitoring Analysis
2 0 1 0 年在北京召开的儿童安全用药国际论坛,来自美国、英国和全国