文档介绍：吲哚布芬治疗心脑血管疾病临床研究
Clinic Analysis of Treatment on the cardiovascular and cerebrovascular diseases with Indobufen
穆建敏朱晓临
河南科技大学洛阳东方医院
摘要:目的:观察吲哚布芬预防心脑血管疾病的有效性和安全性。方法:将入选392例心脑血管疾病患者随机分为观察组(n=196)和对照组(n=196),观察组给予吲哚布芬,对照组给予阿司匹林,进行18个月的观察。结果:观察组和对照组与治疗前相比继发冠心病、心肌梗死、脑梗死的风险明显降低(P<)。两组间比较临床疗效相当(P>),观察组的安全性明显优于对照组。结论:吲哚布芬可有效降低心脑血管疾病患者继发缺血事件的风险,
疗效与阿司匹林相当,但有更好的安全性。
关键词:吲哚布芬,心脑血管疾病,阿司匹林,安全性
〔Abstract〕Objective: To investigate the effects and safety of Xinbei- indobufen in patients with cardiovascular and cerebrovascular diseases. Methods: 392 patients with cardiovascular and cerebrovascular diseases were selected and randomly divided into experiment group (n=196) and control group (n=196). The patients in experiment group were given anti-platelet indobufen , in control group were given aspirin for 18 months. Results: After treatment, the risk of secondary
coronary heart disease,myocardial infarction and cerebral infarction in both groups were lower than before (P<). The overall curative effects were similar in patients of the two groups(P>). But the experiment group was safe then control group. Conclusion: The clinical efficacy were similar in patients with cardiovascular and cerebrovascular diseases between Xinbei- indobufen and aspirin, but the Xinbei- indobufen was more safe.
Key words: Indobufen,cardiovascular and cerebrovascular diseases,Aspirin,Safety
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