文档介绍：颅脑损伤后所致癫痫患者的事件相关电位P300特征
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STRONG【摘要】/STRONG目的探讨颅脑外伤所致癫痫患者的认知功能特点及事件相关电位P300的临床应用价值。方法对53例颅脑外伤所致精神障碍患者、52例颅脑外伤不伴癫痫患者和50例健康对照组分别进行了P300电位测定,采用韦氏成人智力测验修订版测定智商,将三组测定结果进行相关分析。结果颅脑外伤所致癫痫患者组与颅脑外伤组事件相关电位成分中N2、P3波潜伏期延长和P3波幅降低,言语智商、操作智商、总智商得分均降低均较对照组显著,差异均有极显著性(P均<);而颅脑外伤伴癫痫组P300电位成分中N2、P3波潜伏期延长和P3波幅降低及言语智商、操作智商、总智商得分降低均较颅脑外伤组显著,差异均有极显著性(P均<)。相关分析显示,颅脑外伤伴癫痫组P300潜伏期与言语智商、操作智商和总智商分呈显著负相关(r=-~-,P<001),波幅则呈显著正相关(r=~,P<)。结论P300电位是评价颅脑外伤所致癫痫患者认知状况的重要指标。
STRONG【关键词】/STRONG颅脑外伤;癫痫;认知功能;事件相关电位P300
FeaturesofeventrelatedpotentialP300inpatientswithepilepsyduetoheadinjury
ZhangHaoqin,SongJinggui
FengqiuCountyPeople’sProcuratorate,453300,Henan,China
【Abstract】ObjectiveToexplorethefeaturesofcognitioninpatientswithepilepsyduetoheadinjuryandtheclinicalapplicationvalueofeventrelatedpotential(ERP),52oneswithheadinjurewithoutepilepsyand50healthycontrols,IQsdeterminedwiththeWechslerAdultIntelligenceScale(WAIS),andscoresoftheverbal,operationandtotalintelligencequotientsignificantlylowerintheformer2groupsthaninthelatterandinthepatientswithepilepsythanintheoneswithout,differenceswereverysignificant().Correlationanalysessho